LY79771: a novel compound for weight control |
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| Authors: | W N Shaw K K Schmiegel T T Yen R E Toomey D B Meyers J Mills |
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| Institution: | Lilly Research Laboratories, Indianapolis, IN 46285, USA |
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| Abstract: | Compound LY79771 given subcutaneously reduced weight or decreased weight gain of genetically obese rats and mice, gold thioglucose obese mice, and obese beagles. The compound had no effect on body weight of lean rats. Food consumption was not decreased. Obese rats showed a transient rise in body temperature after each administration of the drug. The change in body weight was due mainly to a decrease in body fat mass. |
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