Cell-mediated cytotoxic responses of spleen cells from mice bearing primary, chemically induced tumors. |
| |
Authors: | C I Civin N Dorfman A Eggers K Fink D Penvose C K Hsu J R Wunderlich |
| |
Abstract: | Sarcomas were induced in C57BL/6 mice by using 3-methylcholanthrene. Spleen cells taken from these mice bearing primary, chemically induced tumors and from matched control mice were assessed for the capacity to generate cell-mediated cytotoxic cell activity after in vitro sensitization. Spleen cells from tumor-bearing mice generated strong cell-mediated cytotoxic responses against alloantigens and antigens on syngeneic cells. |
| |
Keywords: | |
|
|