The urbilaterian Super-Hox cluster |
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Authors: | Butts Thomas Holland Peter W H Ferrier David E K |
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Institution: | Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK. |
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Abstract: | Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes). |
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