Dendritic supports in organic synthesis |
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| Authors: | Klein Gebbink Robertus J M Kruithof Cornelis A van Klink Gerard P M Van Koten Gerard |
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| Institution: | Debye Institute, Department of Metal-Mediated Synthesis, Utrecht University, The Netherlands. r.j.m.kleingebbink@chem.uu.nl |
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| Abstract: | An overview is presented of the recent developments in the use of dendritic supports in organic synthesis. Examples are presented of the application of dendritic supports in both liquid- and solid-phase organic synthesis. In liquid-phase synthesis, soluble dendrimers are used as the substrate support, while in solid-phase synthesis, 'dendronized' insoluble resins are used for this purpose. Selected examples of the synthesis of compound libraries on dendritic supports via combinatorial techniques are discussed. |
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