Out-Patient Peritoneal Lavage Cytology In the Detection of Residual Epithelial Ovarian Cancer |
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Authors: | C W E REDMAN S E CHAPMAN S Y CHAN E J BUXTON G BLACKLEDGE D M LUESLEY† |
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Institution: | West Midlands CRC Clinical Trials Unit, Queen Elizabeth Medical Centre, Birmingham, UK. |
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Abstract: | Peritoneal lavage fluid cytology was performed in 87 out-patients with histologically proven epithelial ovarian cancer undergoing primary management. A total of 246 peritoneal lavages were attempted, usually with temporary cannulae (n = 229). From these, 184 samples were obtained, of which 156 (85%) were suitable for cytological analysis. The sensitivity of peritoneal lavage fluid cytology in 67 patients with known residual disease was 57% whereas serum CA 125 levels were elevated in 58 (87%). Pre- and post-treatment peritoneal lavage fluid cytology had prognostic value, but this was less than that of serum CA 125 measurements. |
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Keywords: | ovarian cancer cytology |
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