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AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner |
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| Authors: | Jacob Aaron Klickstein Sirisha Mukkavalli Malavika Raman |
| Affiliation: | Department of Developmental Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, USA |
| Abstract: | |
| Keywords: | protein quality control proteostasis misfolded protein aggregate inclusion body stress granule polyQ inclusion body ubiquitin image-based analysis ImageJ p97/valosin-containing protein microscopic imaging polyubiquitin chain aggregation aggresome protein aggregation Huntington disease amyotrophic lateral sclerosis (ALS) (Lou Gehrig disease) protein misfolding p97/valosin-containing protein |