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GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway
Authors:Jian Lu  Pei Pei Chen  Jia Xiu Zhang  Xue Qi Li  Gui Hua Wang  Ben Yin Yuan  Si Jia Huang  Xiao Qi Liu  Ting Ting Jiang  Meng Ying Wang  Wen Tao Liu  Xiong Zhong Ruan  Bi Cheng Liu  Kun Ling Ma
Affiliation:1.Institute of Nephrology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.;2.John Moorhead Research Laboratory, Department of Renal Medicine, University College London (UCL) Medical School, Royal Free Campus, London, NW3 2PF, UK.
Abstract:
Keywords:diabetic nephropathy   podocytes   lipotoxicity   GPR43   autophagy   low-density lipoprotein receptor
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