Lead resistance and sensitivity in Staphylococcus aureus |
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| Authors: | Hillel S. Levinson Inga Mahler Patricia Blackwelder Terri Hood |
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| Affiliation: | Department of Biology, Brandeis University, Waltham, MA 02254, USA; Rosenstiel School of Marine and Atmospheric Science, University of Miami, Miami, FL 33149, USA |
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| Abstract: | Abstract Five lead-resistant strains of Staphylococcus aureus were isolated. Plasmid-free lead-sensitive variants were obtained from the three plasmid-bearing strains. Lead-resistant strains tolerated an approximately 600 × higher Pb(NO3)2 concentration than lead-sensitive strains. Both types of strains initially bound lead, but only the resistant strains accumulated the metal as an intracellular lead-phosphate. |
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| Keywords: | Staphylococcus aureus Lead resistance Lead uptake |
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