Antibodies to Aeromonas salmonicida Lipopolysaccharide and cell wall antigens in rabbit and salmon immune sera |
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Authors: | Ragnhild Aakre Jakobsen Miguel A. Gutierrez Heidrun I. Wergeland |
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Affiliation: | Department of Fisheries and Marine Biology, University of Bergen, Bergen High Technology Centre, N-5020, Bergen, Norway |
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Abstract: | Atlantic salmon (Salmo salar L.) immunised with A-layer positive or A-layer negative strains ofAeromonas salmonicida did not produce antibodies reactive with proteinase K-digested LPS in the low molecular weight area corresponding to the core-region of LPS. The salmon produced antibody titres as high as those produced by rabbit when assayed against whole bacteria or LPS in ELISA. The salmon antibodies against the A-layer positive strain of A. salmonicida lysed rabbit erythrocytes sensitised with LPS from the A-layer positive strain of A. salmonicida. This was in contrast to the non-haemolytic activity of the salmon antibodies against the A-layer negative strain, indicating differences in epitopes between the two strains. |
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Keywords: | Aeromonas salmonicida antibodies LPS rabbit salmon |
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