Analgesic activity of leaf extracts of Culcasia scandens P. Beauv |
| |
| Authors: | Okoli C O Akah P A Egbuniwe O N |
| |
| Institution: | Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka Enugu State, Nigeria. charlesokoli@hotmail.com |
| |
| Abstract: | Analgesic activity of methanol leaf extract of C. scandens obtained by column chromatography and its graded solvent fractions, was evaluated in mice using acetic acid-induced abdominal writhing and formalin-induced paw licking. The extract and fractions significantly inhibited abdominal writhing and two phases of formalin-induced paw licking in mice, indicating that antinociceptive activity may involve inhibition of pain by peripheral and central mechanisms. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
