Endothelial adhesion molecules in the development of the vascular tree: the garden of forking paths. |
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Authors: | G Bazzoni E Dejana M G Lampugnani |
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Institution: | Laboratory of Vascular Biology Istituto di Ricerche Farmacologiche Mario Negri via Eritrea 62, 20157, Milano, Italy. |
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Abstract: | In the past, year targeted null mutation studies have further supported the concept that endothelial cell-matrix and cell-cell adhesion is involved in the formation and maintenance of the network of branched tubes within the vascular tree. In addition, recent results derived from the closely related experimental system of branching tubulogenesis in epithelial cells may provide an appealing model for endothelial biology. |
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