The Subunit Composition of a GABAA/Benzodiazepine Receptor from Rat Cerebellum |
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| Authors: | Zafar U. Khan Antonia Gutierrez Angel L. De Blas |
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| Affiliation: | Division of Molecular Biology and Biochemistry, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, U.S.A. |
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| Abstract: | Abstract: The pentameric subunit composition of a large population (36%) of the cerebellar granule cell GABAA receptors that show diazepam (or clonazepam)-insensitive [3H]Ro 15-4513 binding has been determined by immunoprecipitation with subunit-specific antibodies. These receptors have α6, α1, γ2S, γ2L, and β2 or β3 subunits colocalizing in the same receptor complex. |
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| Keywords: | Antibody GABA receptor Benzodiazepine receptor Subunit Cerebellum Ro 15-4513 |
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