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On the re-calibration process in radiochromic film dosimetry
Institution:1. Hospital IMED, Servicio de Oncología Radioterápica, Elche (Alicante), Spain;2. Hospital Universitari Sant Joan de Reus, Servicio de Física Médica, Reus (Tarragona), Spain;3. Hospital Universitario Virgen de la Arrixaca, El Palmar (Murcia), Spain;1. Departamento de Fisiología Médica y Biofísica, Universidad de Sevilla, Spain;2. Servicio de Radiofísica, Hospital Universitario Virgen Macarena, Sevilla, Spain;3. Instituto de Física, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile;4. Istituto Nazionale di Fisica Nucleare, Frascati, Italy;1. Department of Medical Physics, Centre Oscar Lambret and University Lille 1, France;2. Academic Department of Radiation Oncology, Centre Oscar Lambret and University Lille 2, France;1. Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan;2. Faculty of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan;3. Department of Health Sciences, School of Medicine, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan;4. Department of Medical Technology, Kyushu University Hospital, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan;5. Saga Heavy Ion Medical Accelerator in Tosu, 415, Harakoga-cho, Tosu 841-0071, Japan;1. School of Health Sciences, University of South Australia, Adelaide, Australia;2. Sansom Institute for Health Research, University of South Australia, Adelaide, Australia;3. School of Physical Sciences, University of Adelaide, Adelaide, Australia;4. The Thailand Office for Peace, Bangkok, Thailand;5. Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide, Australia;6. School of Medicine, University of Adelaide, Adelaide, Australia;7. Faculty of Science, University of Oradea, Oradea 410087, Romania;1. German Cancer Research Center (DKFZ), Division of Medical Physics in Radiation Oncology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany;2. National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg, Germany;3. Heidelberg University Hospital, Department of Radiation Oncology, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany;4. Advacam s.r.o., Na Balkáně 2075/70, 130 00 Praha 3, Czech Republic;5. Institute of Experimental and Applied Physics, Czech Technical University in Prague, Horská 3a/22, 12800 Prague 2, Czech Republic
Abstract:PurposeThe accuracy and precision of the dose estimates obtained with radiochromic film dosimetry are investigated in a clinical environment. The improvement in the accuracy of dose estimates reached with corrective methods is analyzed. Two novel re-calibration algorithms for radiochromic film dosimetry are presented.MethodsTwo different EBT3 lots are evaluated in two different centres. They are calibrated in Varian linacs and read in two different EPSON scaners. Once the lots are calibrated, three films per lot are considered and divided into stripes that are exposed to known doses. Several dosimetry protocols usually employed in radiochromic film dosimetry are used to convert film responses to absorbed doses. These protocols are characterized by different choices of the film responses or different sensitometric curves. Finally, the accuracy and reproducibility of the dose estimates is investigated with and without the corrective methods.Results and ConclusionsThe variabilities that affect radiochromic film dosimetry, such as intra-lot variability, inter-scan variability, post-exposure time and film autodevelopment may give rise to inaccuracies in the dose estimates. However, the implementation of re-calibration methods leads to more accurate dose estimates. All the investigated protocols showed more accurate and reproducible results when the re-calibrated methods were employed. So, the novel re-calibration methods may be applied in order to improve the accuracy and reproducibility of radiochromic film dosimetry.
Keywords:EBT3  Corrective method  Re-calibration  Inter-scan variability  Intra-lot variability
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