Neuromagnetic evidence that the P100 component of the pattern reversal visual evoked response originates in the bottom of the calcarine fissure |
| |
| Institution: | 1. Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA;2. Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children''s Hospital of Philadelphia, Philadelphia, PA 19104, USA;3. Department of Cell Biology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka 573-1010, Japan;4. Children''s Hospital of Philadelphia Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA;5. Department of Pediatric, University of Pennsylvania, Philadelphia, PA 19104, USA;6. Systems Pharmacology and Experimental Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA;1. Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan;2. Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands;3. Department of Neurology, Radboud UMC, Nijmegen, The Netherlands;4. Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan;5. Yoshino Neurology Clinic, Ichikawa, Japan;6. Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan;7. Department of Neurology, National Hospital Organization, Matsue Medical Center, Matsue, Japan;8. Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan;9. Department of Neurology, Vihara Hananosato Hospital, Miyoshi, Japan;10. Department of Neurology, Kitasato University School of Medicine, Kanagawa, Japan;11. Kitasato University, Department of Comprehensive Medicine, Division of Integrated Care and Whole Person Care, Kanagawa, Japan;12. Department of Neurology, Showa University Fujigaoka Hospital, Kanagawa, Japan;13. National Hospital Organization, Sagamihara National Hospital, Kanagawa, Japan;14. Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan;15. Department of Neurology, National Hospital Organization, Higashi Nagoya National Hospital, Nagoya, Japan;p. Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Ehime, Japan;q. Yodoe Clinic, Yonago, Japan;r. Department of Neurology, San-in Rosai Hospital, Yonago, Japan;s. Akasaki Medical Office, Kotoura, Japan;t. Division of Neuropsychiatry, Yowa Hospital, Yonago, Japan;1. Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan;2. North Tohoku Epilepsy Center, Minato Hospital, Hachinohe, Aomori, Japan |
| |
| Abstract: | Visual evoked magnetic fields due to pattern reversal stimuli were measured in 5 normal subjects using a helmet-shaped 66 channel magnetoencephalography system linked to MRI. The magnetic topography of the prominent 100 ms response (P100m) evoked by full-field visual showed a double-dipole pattern in the occipital areas of all subjects. Right or left half-field stimuli and upper or lower quadrant-field stimuli evoked a single-dipole pattern in the contralateral occipital area. The P100m sources were when localized using a current dipole model and superimposed on MRI images of each subject. The visual cortex was morphologically variable among the subjects, but the P100m dipoles were all localized at the lateral bottom of the calcarine fissure. Moreover, these P100m dipoles had similar orientations for both half- or quadrant-field stimuli. These results suggest that the P100m is located in a smaller part of the striate cortex than previously reported. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
