Trends and challenges in phytotherapy and phytocosmetics for skin aging |
| |
Authors: | Idris Adewale Ahmed Maryam Abimbola Mikail Nor Hisam Zamakshshari Mohd Rais Mustafa Najihah Mohd Hashim Rozana Othman |
| |
Institution: | 1. Centre for Natural Products Research and Drug Discovery (CENAR), Level 3, Research Management & Innovation Complex, Universiti Malaya, 50603 Kuala Lumpur, Malaysia;2. Department of Biotechnology, Faculty of Applied Science, Lincoln University College, 47301 Petaling Jaya, Selangor, Malaysia;3. Mimia Skincare Sdn. Bhd., Kuala Lumpur, Malaysia;4. Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Semarahan, Sarawak, Malaysia;5. Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia;6. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia |
| |
Abstract: | Oxidative stress and inflammation mostly contribute to aging and age-related conditions including skin aging. The potential of natural products in the form of naturally-derived cosmetics, cosmeceuticals, and nutricosmetics have, however, not been fully harnessed. This review, thus, critically analyzes the potential roles of natural products in inflammation-related skin aging diseases due to the increasing consumers’ concerns and demands for efficacious, safe, natural, sustainable, and religiously permitted alternatives to synthetic products. The information and data were collated from various resources and literature databases such as PubMed, Science Direct, Wiley, Springer, Taylor and Francis, Scopus, Inflibnet, Google, and Google Scholar using relevant keywords and Medical Subject Headings (MeSH). The role of green extraction solvents as promising alternatives is also elucidated. The potential enhancements of the bioavailability, stability, solubility and controlled release profile of the bioactives using different delivery systems are also presented. The current potential global market value, motivators, drivers, trends, challenges, halal, and other regulatory certifications for cosmeceuticals and nutricosmetics are equally discussed. The adoption of the suggested extractions and delivery systems would enhance the stability, bioavailability, and target delivery of the bioactives. |
| |
Keywords: | Aging Cosmetics Certifications Eutectic solvents Hormesis Inflammation |
本文献已被 ScienceDirect 等数据库收录! |
|