The frequencies of Kidd blood group antigens and phenotypes among Saudi blood donors in Southwestern Saudi Arabia |
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Institution: | 1. Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia;2. SMIRES for Consultation in Specialized Medical Laboratories, Jazan University, Jazan, Saudi Arabia;3. Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia;4. Medical Research Center (MRC), Jazan University, Jazan, Saudi Arabia;5. Department of Laboratory and Blood Bank, Prince Mohammed bin Nasser Hospital, Ministry of Health, Jazan, Saudi Arabia;6. Department of Laboratory and Blood Bank, King Faisal Medical City for Southern Regions, Ministry of Health, Abha, Saudi Arabia;7. Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia |
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Abstract: | BackgroundThe patients who require transfusion are prevalent in the Jazan Province, Saudi Arabia. Therefore, it is essential to know the frequency of blood group antigens in such a population. The Kidd blood group system (JK) has two antithetical antigens, Jka and Jkb. Antibodies to these antigens may result in delayed hemolytic transfusion reactions. The present study investigated the frequencies of Jka and Jkb and the phenotypes among Saudi blood donors living in the Jazan Province.MethodsOne hundred and forty-three samples from anonymous Saudi volunteer blood donors in the Jazan Province were serotype to detect Jka and Jkb using gel card technology and determine the phenotypes of the JK blood group system.ResultsThe prevalence of Jka and Jkb antigens were 90.64% (n = 126) and 69.40% (n = 93), respectively. The JK phenotypes were 34.96% Jk(a + b ? ) (n = 51), 12.59% Jk(a ? b + ) (n = 18), 52.45% Jk(a + b + ) (n = 75), and 0% Jk(a ? b ? ). The frequencies of the JK phenotypes in the Jazan population were significantly different from those in the Asian population (P < 0.05).ConclusionsWe reported the frequencies of the Jka and Jkb antigens and the distribution of the JK phenotypes in a group of Saudi blood donors in the Jazan Province, Saudi Arabia. The phenotype Jk(a + b + ) was the most common among the study population. Furthermore, this study emphasizes the significance of identifying the frequency of JK antigens and phenotypes in the provinces of Saudi Arabia. |
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Keywords: | Kidd blood group Blood donors Immunohematology Saudi Arabia HDFN"} {"#name":"keyword" "$":{"id":"k0030"} "$$":[{"#name":"text" "_":"Hemolytic disease of the fetus and newborn HTR"} {"#name":"keyword" "$":{"id":"k0040"} "$$":[{"#name":"text" "_":"Hemolytic transfusion reactions RBC"} {"#name":"keyword" "$":{"id":"k0050"} "$$":[{"#name":"text" "_":"Red blood cell SNP"} {"#name":"keyword" "$":{"id":"k0060"} "$$":[{"#name":"text" "_":"Single nucleotide polymorphism |
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