Exercise might favor reverse cholesterol transport and lipoprotein clearance: potential mechanism for its anti-atherosclerotic effects |
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| Authors: | Wei Chen Penumetcha Meera Santanam Nalini Liu Ya-Guang Garelnabi Mahdi Parthasarathy Sampath |
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| Institution: | Department of Cardiology, Emory University, Atlanta, GA 30322, United States. |
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| Abstract: | Livers of C57 BL/6 mice exercised for 2 weeks showed a dramatic increase in scavenger receptor B1 (SR-B1), CD36 and low density lipoprotein (LDL) receptor and a decrease in acetyl LDL receptor gene expression. These effects on lipoprotein receptors are reminiscent of the effects mediated by peroxisome proliferator-activated receptor (PPARgamma) ligands. |
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