Diffusible signal factor-dependent cell-cell signaling and virulence in the nosocomial pathogen Stenotrophomonas maltophilia |
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| Authors: | Fouhy Yvonne Scanlon Karl Schouest Katherine Spillane Charles Crossman Lisa Avison Matthew B Ryan Robert P Dow J Maxwell |
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| Institution: | BIOMERIT Research Centre, Department of Microbiology, BioSciences Institute, National University of Ireland, Cork, Ireland. |
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| Abstract: | The genome of Stenotrophomonas maltophilia encodes a cell-cell signaling system that is highly related to the diffusible signal factor (DSF)-dependent system of the phytopathogen Xanthomonas campestris. Here we show that in S. maltophilia, DSF signaling controls factors contributing to the virulence and antibiotic resistance of this important nosocomial pathogen. |
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