New bulky chiral Lewis acid catalyst: 3,3'-di(2-mesitylethynyl)binaphthol-titanium(IV) complex |
| |
| Authors: | Ishihara Kazuaki Kobayashi Jun Nakano Kazuhiko Ishibashi Hideaki Yamamoto Hisashi |
| |
| Affiliation: | Graduate School of Engineering, Nagoya University, SORST, Japan Science and Technology Corporation (JST), Furo-cho, Chikusa 464-8603, Nagoya, Japan. |
| |
| Abstract: | A new chiral Lewis acid catalyst 9 was prepared in situ from a 1:2 molar mixture of (R)-3,3'-di(2-mesitylethynyl)binaphthol (6) and titanium(IV) isopropoxide at ambient temperature. The 3- and 3'-substituents on 6 were effective for preventing undesired aggregation between Ti(IV) complexes and increasing the enantioselectivity (up to 82% ee) in the Diels-Alder reaction of methacrolein with cyclopentadiene. |
| |
| Keywords: | chiral Lewis acid Diels‐Alder reaction titanium (IV) enantioselective binaphthol |
| 本文献已被 PubMed 等数据库收录！ |
|
