Chemical composition and antimicrobial activity of the essential oil of Cacalia tangutica (Maxim.) Hand.-Mazz |
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Authors: | Yang Yang Shunying Zhu Xiaoqiang Cai Lifei Tang Deqing Liu Jinghua Huang Guolin Zou |
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Affiliation: | 1. College of Life Sciences, Wuhan University/State Key Laboratory of Virology, Wuhan, 430072, China 2. Wuhan Huazhen Pharmaceutical Company Limited, Wuhan, 430051, China
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Abstract: | Essential oil of the subterranean part of Cacalia tangutica (Maxim.) Hand.-Mazz was analyzed by gas chromatography (GC)-mass spectrum (MS) tech-nique in two different capillary columns of different polar-ities. Thirty-one components were identified in the oil and the main compounds were a-zingiberene (13.49%), germa-crene D (10.76%), a-pinene (8.54%), caryophyllene(Z-) (6.36%), linalool (6.16%), β-myrcene (4.89%),β-ocimene (Z-) (4.40%)and ocimenone(Z-) (3.58%). The antimicro-bial activity of the oil was evaluated against 2 fungi and 12 bacteria including 6 clinically isolated strains using the agar disc diffusion and broth microdilution methods. The results show that the oil presented a broad antimicro-bial spectrum and had better antimicrobial activity against yeast and gram-positive bacteria. The minimum inhibitory concentration values were 0.16-5.00 g/L and minimum bactericidal concentration values were 0.16-5.00 g/L. |
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Keywords: | Cacalia tangutica antimicrobial activity essential oil gas chromatography (GC)-mass spectrum (MS) |
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