Mapping of the Mouse Actin Capping Protein Beta Subunit Gene |
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Authors: | Marilyn C Hart Yulia O Korshunova John A Cooper |
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Institution: | (1) Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110, USA;(2) Winona State University, Winona, MN 55987, USA;(3) Department of Genetics, Washington University, St. Louis, MO 63110, USA |
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Abstract: | Background Capping protein (CP), a heterodimer of α and β subunits, is found in all eukaryotes. CP binds to the barbed ends of actin filaments in vitro and controls actin assembly and cell motility in vivo. Vertebrates have three isoforms of CPβ produced by alternatively splicing from one gene; lower organisms have one gene and one isoform. |
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