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Microencapsulation of insulin microcrystals
Authors:Choi Sung Hee  Kwon Jai-Hyun  Kim Chan-Wha
Institution:Graduate School of Life Sciences and Biotechnology, Korea University, Seoul, Korea.
Abstract:Insulin microcrystals were encapsulated (microcrystal/PLGA) within poly(lactide-co-glycolide) (PLGA 50:50) by the multiple emulsification solvent evaporation technique and compared with insulin solution microspheres (solution/PLGA) in terms of their morphology, size distribution, drug content, encapsulation efficiency, and stability of insulin during release.
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