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Massively parallel characterization of CYP2C9 variant enzyme activity and abundance
Authors:Clara J. Amorosi  Melissa A. Chiasson  Matthew G. McDonald  Lai Hong Wong  Katherine A. Sitko  Gabriel Boyle  John P. Kowalski  Allan E. Rettie  Douglas M. Fowler  Maitreya J. Dunham
Affiliation:1. Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA;2. Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA;3. Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
Abstract:
Keywords:CYP2C9  deep mutational scanning  pharmacogenomics  warfarin  humanized yeast
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