Muscle provocation test. A sensitive method for discrimination between carriers and noncarriers of Duchenne muscular dystrophy |
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| Authors: | F H Herrmann A Spiegler G Wiedemann |
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| Institution: | (1) Abteilung Medizinische Genetik, Medizinische Akademie Erfurt, Klement-Gottwald-Str. 34, DDR-5080 Erfurt, German Democratic Republic;(2) Kinderklinik, Am Schwemmbach 32a, DDR-5080 Erfurt, German Democratic Republic |
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| Abstract: | Summary After 40 min of strenuous exercise on a bicycle ergometer (muscle provocation test, MPT), normal women and obligate carriers showed a progressive elevation of serum creatine kinase, with a peak 8 h after exercise. The diagnostic applicability of MPT for carrier detection is demonstrated. |
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