Ion transport systems in erythrocyte membrane of spontaneously hypertensive rats (SHR) as compared with normotensive rats of the Brown Norway (BN.lx) strain. |
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| Authors: | S N Orlov N I Pokudin Kunes" target="_blank">J Postnov YuVKunes J Zicha |
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| Institution: | School of Biology, Moscow State University. |
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| Abstract: | The activity of Na+, K(+)-ATPase in SHR erythrocytes treated with saponin is increased by 30-40% as compared to the Brown Norway (BN.lx) strain whereas the activity of Ca(2+)-ATPase is decreased by 20-30%. Passive permeability of SHR erythrocytes determined by 86Rb influx is increased by 20-30%. In the presence of orthovanadate erythrocytes of SHR accumulate 45Ca by 80% more than BN.lx red cells. There was no difference in Na+/H+ exchange between erythrocytes of SHR and BN.lx animals. |
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