Lipid peroxidation, vitamins C, E and reduced glutathione levels in patients with pulmonary tuberculosis |
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Authors: | Vijayamalini M Manoharan S |
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Affiliation: | Department of Biochemistry, Faculty of Science, Annamalai University, Annamalai Nagar, Tamil Nadu, India. |
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Abstract: | The present study examined the relationship between lipid peroxidation and vitamin C, vitamin E and reduced glutathione levels in plasma, erythrocytes and erythrocyte membranes of pulmonary tuberculosis patients and an equal number of age-and sex-matched healthy subjects. Enhanced plasma, erythrocytes and erythrocyte membrane lipid peroxidation with concomitant decline in vitamin C, vitamin E and reduced glutathione levels were found in pulmonary tuberculosis patients. The elevated lipid peroxidation and decreased vitamin C, vitamin E and reduced glutathione levels indicate the potential of oxidative damage to erythrocytes and erythrocyte membranes of pulmonary tuberculosis patients. |
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Keywords: | tuberculosis lipid peroxidation vitamin C vitamin E reduced glutathione |
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