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Infectivity of Leishmania donovani Amastigotes and Promastigotes for Golden Hamsters*
Authors:JAN S. KEITHLY
Abstract:SYNOPSIS. Intracardial injection of hamsters with from 5 to 114 million amastigotes or promastigotes of Leishmania donovani and screening of the 8th-day liver impression smears, provides a rapid and reproducible method for assaying infectivity. Amastigotes are at least 10X more infective than promastigotes, and log-phase promastigotes act as a single infective population for hamsters.
Keywords:Leishmania donovani  amastigotes  promastigotes  infectivity for hamsters  infectivity assay
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