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Cartilage intermediate layer protein promotes lumbar disc degeneration
Authors:Shoji Seki  Noriyuki Tsumaki  Hiraku Motomura  Makiko Nogami  Yoshiharu Kawaguchi  Takeshi Hori  Kayo Suzuki  Yasuhito Yahara  Mami Higashimoto  Takeshi Oya  Shiro Ikegawa  Tomoatsu Kimura
Affiliation:1. Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama 930-0194, Japan;2. Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan;3. Department of Pathology, Niigata Prefectural Central Hospital, 205 Shinminamimachi, Joetsu, Niigata 943-0192, Japan;4. Laboratory for Bone and Joint Diseases, SNP Research Center, RIKEN, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
Abstract:
Keywords:Cartilage intermediate layer protein   Tissue specific promoter   Transgenic mice   Transforming growth factor-beta   Lumbar disc degeneration
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