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Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity |
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| Authors: | Yutaka Sasaki Michinori Kakisaka Nopporn Chutiwitoonchai Shigeru Tajima Hirokazu Hikono Takehiko Saito Yoko Aida |
| Institution: | 1. Viral Infectious Diseases Unit, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan;2. Department of Virology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku, Tokyo 162-8640, Japan;3. Influenza and Prion Disease Research Center, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan |
| Abstract: | |
| Keywords: | Anti-influenza viral drug Compound library screening vRNP activity Kinase inhibitor Target database search KINOMEscan |
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