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Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes |
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| Authors: | Beate Rockel Tilo Schmaler Xiaohua Huang Wolfgang Dubiel |
| Institution: | 1. Department of Molecular Structural Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany;2. Division of Molecular Biology, Department of General, Visceral, Vascular and Thoracic Surgery, Charité – Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany |
| Abstract: | |
| Keywords: | COP9 signalosome Lid Deneddylation Cryo-electron microscopy 3D-reconstruction Single-particle analysis |
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