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Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins |
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| Authors: | Min-Sung Lee Ji-Hyang Ha Ho Sup Yoon Chong-Kil Lee Seung-Wook Chi |
| Affiliation: | 1. Medical Proteomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea;2. Department of Bio-Analytical Science, University of Science and Technology, Daejeon 305-350, Republic of Korea;3. College of Pharmacy, Chungbuk National University, Cheongju 361-763, Republic of Korea;4. Division of Structural Biology and Biochemistry, School of Biological Sciences, Nanyang Technological University, Singapore 637511, Singapore |
| Abstract: | |
| Keywords: | p53 transactivation domain MDM2-inhibiting peptide Bcl-2 family proteins NMR spectroscopy Dual-targeting Cancer therapy |
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