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Effect of biofilm growth on expression of surface proteins of Actinomyces naeslundii genospecies 2
Authors:Paddick James S  Brailsford Susan R  Rao Susmitha  Soares Renata F  Kidd Edwina A M  Beighton David  Homer Karen A
Affiliation:Department of Microbiology, King's College Dental Institute at Guy's, King's College and St. Thomas' Hospitals, Floor 17, Guy's Tower, Guy's Hospital, London SE1 9RT, United Kingdom.
Abstract:The predominant surface proteins of biofilm and planktonic Actinomyces naeslundii, a primary colonizer of the tooth surface, were examined. Seventy-nine proteins (the products of 52 genes) were identified in biofilm cells, and 30 of these, including adhesins, chaperones, and stress-response proteins, were significantly up-regulated relative to planktonic cells.
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