Mechanisms of DNA bending |
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| Authors: | L James Maher III |
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| Institution: | Department of Biochemistry and Molecular Biology, Mayo Foundation, GU16, 200 First Street SW, Rochester, MN 55905, USA |
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| Abstract: | Genome packaging and gene regulation require DNA bending. Recent developments in the elucidation of the mechanisms involved in DNA bending include new X-ray structures (most notably that of the mammalian nucleosome) wherein DNA is bent, controversy surrounding interpretation of DNA-bending experiments with basic-leucine zipper proteins, studies of electrostatic effects in DNA bending, and the design of artificial DNA-bending ligands. |
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| Keywords: | Abbreviations: bZIP basic leucine zipper CAP catabolite activator protein TBP TATA box binding protein |
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