Sex chromosomes: Evolving dosage compensation |
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| Authors: | Brian Charlesworth[Author vitae] |
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| Affiliation: | 1Institute of Cell, Animal and Population Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh EH9 2BR, UK |
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| Abstract: | Dosage compensation of some X-linked genes varies among mammals. Inactivation of an X-linked copy of a gene in females appears to correlate with lack of an active homologue on the Y chromosome, implying that dosage compensation evolves in response to the loss of function of genes on the Y. |
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