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RNA catalysis
Authors:William G Scott
Institution:Department of Chemistry and Biochemistry and The Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California Santa Cruz, Santa Cruz, CA 95064, USA
Abstract:Our understanding of the relationship between the structure of RNA and its catalytic activity has advanced significantly in the past year. These advances include time-resolved crystallographic studies on the hammerhead ribozyme, as well as new structures of a group I intron, a lead(II)-cleavage ribozyme, a hepatitis delta virus ribozyme, and components of the spliceosome machinery and the peptidyl transferase center of the ribosome and, most significantly, the structure of the ribosome itself.
Keywords:Abbreviations: HDV hepatitis delta virus  snRNA small nuclear RNA  VS varkud satellite
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