| 我国一例典型艾滋病家庭的确认及其病毒env基因片段的序列分析 |
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| 引用本文： | 林旭东,孙峰.我国一例典型艾滋病家庭的确认及其病毒env基因片段的序列分析[J].病毒学报,1999,15(1):7-13. |
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| 作者姓名： | 林旭东 孙峰 |
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| 作者单位： | [1]卫生部艾滋病预防与控制中心 [2]伊犁自治州卫生防疫站 |
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| 摘 要： | 报道一例我国典型的ＨＩＶ感染家庭，其中对新生儿通过垂直传播感染的早期诊断为我国首例报道。父亲通过静脉吸毒感染ＨＩＶ，经性途径传播给妻子，并通过母婴途径传播至婴儿，导致婴儿发病。通过血清学、ＰＣＲ检测和病毒培养确认为整个家庭的感染。序列分析结果强烈支持杂来自同一毒株，流行背景主实了上述感染的传播途径。
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| 关 键 词： | 人免疫缺陷病毒 序列分析 垂直传播 |
CONFIRMATION OF A TYPICAL HIV INFECTED CHINESE FAMILY AND SEQUENCE ANALYSIS
OF THE env GENE SEGMENT |
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| Lin Xudong,Sun Feng,Pan Pinlinag,Xing Hui,Dong Wenping,Zhang Yanzhi,Shao Yiming.CONFIRMATION OF A TYPICAL HIV INFECTED CHINESE FAMILY AND SEQUENCE ANALYSIS
OF THE env GENE SEGMENT[J].Chinese Journal of Virology,1999,15(1):7-13. |
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| Authors: | Lin Xudong Sun Feng Pan Pinlinag Xing Hui Dong Wenping Zhang Yanzhi Shao Yiming |
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| Institution: | Lin Xudong 1 Sun Feng 2 Pan Pinlinag 1 Xing Hui 1
Dong Wenping 1 Zhang Yanzhi 3 Shao Yiming 1 |
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| Abstract: | One typical HIV infected
Chinese family was reported. The husband was HIV 1 infected by drug abuse and transmitted
to his wife. Then the wife transmitted to their newborn by vertical transmission. Serum test, PCR
test and viral culture confirmed their infection. Sequences of HIV env gene were analyzed.
Laboratory data strongly indicate three infections were induced by one strain of HIV 1. The
epidemiology investigation confirmed the pathway of transmission. |
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| Keywords: | Human immunodeficiency virus Sequence analysis Vertical transmission |
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