A DNA ligase from mitochondria of rat liver. |
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| Authors: | C J Levin S B Zimmerman |
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| Affiliation: | Laboratory of Molecular Biology National Institute of Arthritis, Metabolism and Digestive Diseases National Institutes of Health Bethesda, Maryland 20014 USA |
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| Abstract: | An ATP-dependent DNA ligase has been demonstrated in extracts of rat liver mitochondria. The activity may be released from the mitochondria by treatment with hypotonic solutions or a detergent, indicating an intramitochondrial localization. The properties of the partially purified enzyme are similar to those of the nuclear DNA ligase from rat liver. |
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