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Dendritic ventriloquism: inhibitory synapses throw their voices
Authors:Sarah Rieubland  Arnd Roth  Michael Häusser
Affiliation:Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.
Abstract:In a theoretical study in this issue of Neuron,Gidon and Segev (2012) identify several new principles governing how inhibition interacts with excitation in active dendrites. They show that inhibitory synapses can interact with excitability at a distance, effectively "throwing their voices" in the dendritic tree, such that distributed inhibitory synapses can act synergistically to provide a global veto of dendritic excitability.
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