Protein metal-binding sites. |
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| Authors: | J A Tainer V A Roberts E D Getzoff |
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| Affiliation: | Department of Molecular Biology, Scripps Research Institute, La Jolla, CA 92037. |
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| Abstract: | Metal ions have a role in a variety of important functions in proteins including protein folding, assembly, stability, conformational change, and catalysis. The presence or absence of a given metal ion is crucial to the conformation or activity of over one third of all proteins. Recent developments have been made in the understanding and design of metal-binding sites in proteins, an important and rapidly advancing area of protein engineering. |
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