Alterations in the hepatic enzymes following experimental lead poisoning |
| |
Authors: | B Nehru S Kaushal |
| |
Institution: | (1) Department of Biophysics, Panjab University, 160014 Chandigarh, India |
| |
Abstract: | An investigation on the influence of lead toxicity on some of the hepatic enzymes was studied in rats both after a shorter
interval of 15 d and after longer intervals of 60 and 90 d. Three different doses of lead as 5, 10, and 50 mg/kg body wt were
administered orally on every alternate day. Whereas significant inhibition of succinic dehydrogenase was seen following lead
poisoning, the activity acid and alkaline phosphatase increased with lead intoxication. The histoarchitecture of the liver
was grossly intact. Liver accumulated less lead compared to kidney at 60 and 90 d. |
| |
Keywords: | Lead acetate liver enzymes lead concentration |
本文献已被 SpringerLink 等数据库收录! |
|