Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus |
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| Authors: | Schneider Johannes Yepes Ana Garcia-Betancur Juan C Westedt Isa Mielich Benjamin López Daniel |
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| Affiliation: | Institute for Molecular Infection Biology IMIB, Centre for Molecular Research in Infectious Disease ZINF, University of Würzburg, Würzburg, Germany |
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| Abstract: | Bacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus. ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. |
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