Mechanically improved electrospun PCL biocomposites reinforced with a collagen coating process: preparation, physical properties, and cellular activity |
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Authors: | Soon Gee Hong Geun Hyung Kim |
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Affiliation: | 1. Department of Mechanical Engineering, Chosun University, Gwangju, South Korea 2. CG-Bio Inc, Sandawon-dong, Jungwon-Gu, SungNam, Gyounggi-Do, South Korea
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Abstract: | In this work, we fabricated highly aligned electrospun poly(ε-caprolactone)(PCL)/collagen biocomposites, which were consisted of multi-layered structure. The aligned directions of the composites were controlled with two rotating collectors, and various weight fractions (1, 2, 3 wt%) of collagen were embedded between the mat of PCL microfibers to improve the mechanical property and biological activities of osteoblast-like cells (MG63). The PCL/collagen biocomposite showed nine times of increment in mechanical strength of random PCL/collagen composite. An increase in collagen content in the biocomposites displayed significant increase of mechanical properties, hydrophilic property, water-absorption ability, and even cell viability of osteoblast-like cells (MG63). |
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