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Na+ dependence of phenacetin absorption
Authors:Moro E  Guiso R  Cantone A
Affiliation:Department of Nutritional Physiology, Medical School of the University of Milan.
Abstract:Phenacetin in solution at different concentrations of Na+ was orally administered to dogs. Phenacetin absorption is increased by the Na+: a positive correlation was noted between the Na+ concentration in the medium and the plasma levels of phenacetin. Ouabain antagonizes the effect of Na+ on phenacetin absorption.
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