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Unsuspected Dengue as a Cause of Acute Febrile Illness in Children and Adults in Western Nicaragua
Authors:Megan E Reller  Aravinda M de Silva  Jeremy J Miles  Ramesh S Jadi  Anne Broadwater  Katie Walker  Christopher Woods  Orlando Mayorga  Armando Matute
Abstract:BackgroundDengue is an emerging infectious disease of global significance. Suspected dengue, especially in children in Nicaragua’s heavily-urbanized capital of Managua, has been well documented, but unsuspected dengue among children and adults with undifferentitated fever has not.Conclusions/SignificanceDengue is an important and largely unrecognized cause of fever in rural western Nicaragua. Since Zika virus is transmitted by the same vector and has been associated with severe congenital infections, the population we studied is at particular risk for being devastated by the Zika epidemic that has now reached Central America.
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