Evolutionary models for insertions and deletions in a probabilistic modeling framework |
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| Authors: | Email author" target="_blank">Elena?RivasEmail author |
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| Institution: | (1) Department of Genetics, Washington University School of Medicine, 4444 Forest Park Blvd., Saint Louis, Missouri 63108, USA |
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| Abstract: | Background Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and
mRNAs, or their context-free grammar counterparts for structural RNAs) often assume a fixed degree of divergence. Ideally
we would like these models to be conditional on evolutionary divergence time. |
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