Effect of temperature upon heart preservation for transplantation. |
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| Authors: | L H Toledo-Pereyra M Chee R C Lillehei |
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| Institution: | 1. Department of Surgery, Sections of Transplantation and Surgical Research, Henry Ford Hospital, Detroit, Michigan U.S.A.;2. Department of Surgery, University of Minnesota, Minneapolis, Minnesota U.S.A. |
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| Abstract: | In this work we studied the effect of three different temperatures (7 °, 15 °, and 30 °C) on heart preservation. The best temperature for 24 hr pulsatile perfusion of canine hearts was 7 °C. Hearts perfused at this temperature showed no evidence of abnormal preservation changes nor of histological damage immediately upon transplantation. If the temperature was increased to 15 ° or 30 °C, moderate to severe preservation and histological damage were observed, and only three out of 10 dogs survived upon heart implantation. |
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