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乳酸菌代谢组学研究进展
引用本文:孙茂成,李艾黎,霍贵成,孟祥晨. 乳酸菌代谢组学研究进展[J]. 微生物学通报, 2012, 39(10): 1499-1505
作者姓名:孙茂成  李艾黎  霍贵成  孟祥晨
作者单位:东北农业大学乳品科学教育部重点实验室 东北农业大学 食品学院 黑龙江 哈尔滨 150030
基金项目:教育部创新团队科学基金资助项目(No. IRT-0959-205); 国家自然科学青年基金项目(No. 31101267)
摘    要:代谢组学作为系统生物学的重要分支,近年来在微生物研究领域受到广泛关注,并取得了重要进展。目前乳酸菌代谢组学正日益成为研究的热点,就乳酸菌代谢组学研究中有关样品的制备、分析鉴定和数据分析等涉及的主要方法进行概述,并介绍一些乳酸菌代谢组学应用的典型实例,对乳酸菌代谢组学研究中潜在的问题和未来发展趋势进行讨论。

关 键 词:乳酸菌  代谢组学  应用

Progress on the metabolomics of lactic acid bacteria
SUN Mao-Cheng,LI Ai-Li,HUO Gui-Cheng and MENG Xiang-Chen. Progress on the metabolomics of lactic acid bacteria[J]. Microbiology China, 2012, 39(10): 1499-1505
Authors:SUN Mao-Cheng  LI Ai-Li  HUO Gui-Cheng  MENG Xiang-Chen
Affiliation:Key Laboratory of Dairy Science, Ministry of Education, and Food Science College, Northeast Agricultural University, Harbin, Heilongjiang 150030, China
Abstract:Metabolomics is an important branch of systematic biology. It has received great attention around the world, especially in microbiological research field, and new progress has been also made. The metabolomics of lactic acid bacteria has become one of the hottest research topics. This review summarizes the major techniques involved in the research procedures of the metabolomics of lactic acid bacteria, including sample preparation, analysis and identification of metabolites and data analysis. The applications of the metabolomics of lactic acid bacteria are also given based on several typical examples. At the same time, we discussed the potential problems of the metabolomics of lactic acid bacteria, and points out the future of this research.
Keywords:Lactic acid bacteria   Metabolomics   Application
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