Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2 |
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Authors: | H Christian Reinhardt Michael B Yaffe |
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Affiliation: | 1. David H. Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States;2. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States;1. Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, Mary-Jean Mitchell Green Building, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK;2. Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia;3. Department of Medical Biology, University of Melbourne, Parkville, VIC 3050, Australia;4. Institute for Genetics, University of Cologne, 50931 Cologne, Germany;5. Centre for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany;6. Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany;1. Department of Molecular Biology, University of Geneva, 30 Quai Ernest-Ansermet, 1211 Geneva, Switzerland;2. Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece;3. School of Pharmaceutical Sciences, Department of Pharmaceutical Biochemistry, CMU, University of Geneva and University of Lausanne, Rue Michel-Servet 1, 1211 Geneva, Switzerland;4. Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark;5. Faculty Institute for Cancer Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M13 9PL, UK;6. Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece;1. DNA Damage Response Laboratory, London Research Institute, Cancer Research UK, Clare Hall, South Mimms, London EN6 3LD, UK;2. Lymphocyte Interaction Group, London Research Institute, Cancer Research UK, 44 Lincoln’s Inn Field, London WC2A 3LY, UK;3. Institute of Molecular Cancer Research, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland;4. MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK;1. Center for Chromosome Stability and Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen N, Denmark;1. Center for Gastric Cancer Research of Hunan Province, First Affiliated Hospital, University of South China, Hengyang, Hunan 421001, China;2. Key Laboratory of Cancer Cellular and Molecular Pathology of Hunan Provincial University, Cancer Research Institute, University of South China, Hengyang, Hunan 421001, China;3. Key Laboratory for Pharmacoproteomics of Hunan Provincial University, Institute of Pharmacy and Pharmacology, University of South China, Hengyang, Hunan 421001, China;1. Department I of Internal Medicine, University Hospital Cologne, Weyertal 115B, 50931 Cologne, Germany;2. CECAD, University of Cologne, Weyertal 115B, 50931 Cologne, Germany;3. Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany;4. Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany;5. The Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, UK;6. Institute of Pathology, University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany;7. Network Genomic Medicine, University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany;8. Lungenklinik, Krankenhaus Bethanien Moers, Bethanienstraße 21, 47441 Moers, Germany;9. Klinik für Pneumologie, Krankenhaus Bethanien Solingen, Aufderhöher Strasse 169-175, 42699 Solingen, Germany;10. Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany;11. Department of Radiology, University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany;12. Department of Dermatology, University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany;13. Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark;14. Institute of Molecular and Translational Medicine, Palacky University, Hněvotínská 1333/5, 77900 Olomouc, Czech Republic;15. Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden;16. German Cancer Consortium, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany;17. Department of Internal Medicine II, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675 München, Germany;18. Department of Translational Genomics, Medical Faculty, University of Cologne, Weyertal 115B, 50931 Cologne, Germany |
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