Impedance Analysis of Complex Formation Equilibria in Phosphatidylcholine Bilayers Containing Decanoic Acid or Decylamine |
| |
| Authors: | Monika Naumowicz Aneta Dorota Petelska Zbigniew Artur Figaszewski |
| |
| Institution: | (1) Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443 Bialystok, Poland;(2) Laboratory of Electrochemical Power Sources, Faculty of Chemistry, University of Warsaw, Pasteur Street 1, 02-093 Warsaw, Poland |
| |
| Abstract: | Bilayer lipid membranes composed of phosphatidylcholine and decanoic acid or phosphatidylcholine and decylamine were investigated
using electrochemical impedance spectroscopy. Interaction between membrane components causes significant deviations from the
additivity rule. Area, capacitance, and stability constant values for the complexes were calculated based on the model assuming
1:1 stoichiometry, and the model was validated by comparison of these values to experimental results. We established that
phosphatidylcholine and decylamine form highly stable 1:1 complexes. In the case of decanoic acid-modified phosphatidylcholine
membranes, complexes with stoichiometries other than 1:1 should be taken into consideration. |
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
