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The epigenome of Trypanosoma brucei: A regulatory interface to an unconventional transcriptional machine
Authors:Johannes P. Maree  Hugh -G. Patterton
Affiliation:Advanced Biomolecular Research Cluster, University of the Free State, PO Box 339, Bloemfontein 9332, South Africa
Abstract:The epigenome represents a major regulatory interface to the eukaryotic genome. Nucleosome positions, histone variants, histone modifications and chromatin associated proteins all play a role in the epigenetic regulation of DNA function.
Keywords:Epigenetics   Chromatin   Transcription   Gene regulation   African sleeping sickness
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