The epigenome of Trypanosoma brucei: A regulatory interface to an unconventional transcriptional machine |
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Authors: | Johannes P. Maree Hugh -G. Patterton |
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Affiliation: | Advanced Biomolecular Research Cluster, University of the Free State, PO Box 339, Bloemfontein 9332, South Africa |
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Abstract: | The epigenome represents a major regulatory interface to the eukaryotic genome. Nucleosome positions, histone variants, histone modifications and chromatin associated proteins all play a role in the epigenetic regulation of DNA function. |
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Keywords: | Epigenetics Chromatin Transcription Gene regulation African sleeping sickness |
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